Recombinant Human Protein DEPP (DEPP)

Code CSB-YP865135HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP865135HU
MSDS
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Source E.coli
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Code CSB-EP865135HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP865135HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP865135HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
DEPP1
Uniprot No.
Alternative Names
Decidual protein induced by progesterone; Depp; DEPP_HUMAN; Fasting-induced gene protein; FIG; Protein DEPP
Species
Homo sapiens (Human)
Expression Region
1-212
Target Protein Sequence
MRSRLLLSVA HLPTIRETTE EMLLGGPGQE PPPSPSLDDY VRSISRLAQP TSVLDKATAQ GQPRPPHRPA QACRKGRPAV SLRDITARFS GQQPTLPMAD TVDPLDWLFG ESQEKQPSQR DLPRRTGPSA GLWGPHRQMD SSKPMGAPRG RLCEARMPGH SLARPPQDGQ QSSDLRSWTF GQSAQAMASR HRPRPSSVLR TLYSHLPVIH EL
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
Gene References into Functions
  1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
  2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
  3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
  4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
  5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
  6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073

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Subcellular Location
Cytoplasm. Peroxisome. Mitochondrion.
Tissue Specificity
Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
Database Links

HGNC: 23355

OMIM: 611309

KEGG: hsa:11067

STRING: 9606.ENSP00000298295

UniGene: Hs.93675

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