DET1 Antibody

Code CSB-PA762572LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA762572LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA762572LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DET1 Polyclonal antibody
Uniprot No.
Target Names
DET1
Alternative Names
DET1 antibody; DET1 homolog antibody; De-etiolated-1 homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human DET1 homolog protein (5-190AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DET1 Antibody (Product code: CSB-PA762572LA01HU) is Non-conjugated. For DET1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA762572LB01HU DET1 Antibody, HRP conjugated ELISA
FITC CSB-PA762572LC01HU DET1 Antibody, FITC conjugated
Biotin CSB-PA762572LD01HU DET1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.
Gene References into Functions
  1. promotes ubiquitination and degradation of c-Jun by assembling a multisubunit ubiquitin ligase containing DNA Damage Binding Protein-1 (DDB1), cullin 4A (CUL4A), Regulator of Cullins-1 (ROC1), and constitutively photomorphogenic-1 PMID: 14739464
  2. These findings demonstrate that the conserved DET1 complex modulates Cul4A functions by a novel mechanism. PMID: 17452440
Subcellular Location
Nucleus.
Protein Families
DET1 family
Tissue Specificity
Highly expressed in the ovary, some lymphoid organs and resting leukocytes.
Database Links

HGNC: 25477

OMIM: 608727

KEGG: hsa:55070

STRING: 9606.ENSP00000408994

UniGene: Hs.655064

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