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DNASE2B Antibody, Biotin conjugated

Datasheet
Code CSB-PA841227LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DNASE2B Polyclonal antibody
Uniprot No.
Q8WZ79
Target Names
DNASE2B
Alternative Names
DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Gene References into Functions
  1. HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
  2. These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
  3. gene lie head-to-head with the urate oxidase gene PMID: 11700027
Subcellular Location
Lysosome.
Protein Families
DNase II family
Tissue Specificity
Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
Database Links

HGNC: 28875

OMIM: 608057

KEGG: hsa:58511

STRING: 9606.ENSP00000359699

UniGene: Hs.129142

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