DNASE2B Antibody, HRP conjugated

Datasheet
Code CSB-PA841227LB01HU
Size US$299
Uniprot No. Q8WZ79
Protocols ELISA Protocol
Immunogen Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD), DNASE2B, DLAD
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names DNASE2B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Subcellular Location Lysosome
Protein Families DNase II family
Tissue Specificity Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
Database Links

HGNC: 28875

OMIM: 608057

KEGG: hsa:58511

STRING: 9606.ENSP00000359699

UniGene: Hs.129142

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