DNASE2B Antibody

Code CSB-PA841227LA01HU
Size US$299
Image
  • Western Blot
    Positive WB detected in: A549 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
    All lanes: DNASE2B antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 42, 18 kDa
    Observed band size: 42 kDa
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) DNASE2B Polyclonal antibody
Uniprot No. Q8WZ79
Target Names DNASE2B
Alternative Names DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Gene References into Functions
  1. HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
  2. These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
  3. gene lie head-to-head with the urate oxidase gene PMID: 11700027
Subcellular Location Lysosome
Protein Families DNase II family
Tissue Specificity Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
Database Links

HGNC: 28875

OMIM: 608057

KEGG: hsa:58511

STRING: 9606.ENSP00000359699

UniGene: Hs.129142

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