DNASE2B Antibody

Datasheet

Code	CSB-PA841227LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: A549 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate All lanes: DNASE2B antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 42, 18 kDa Observed band size: 42 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DNASE2B Polyclonal antibody

Uniprot No.

Q8WZ79

Target Names

DNASE2B

Alternative Names

DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DNASE2B Antibody (Product code: CSB-PA841227LA01HU) is Non-conjugated. For DNASE2B Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA841227LB01HU	DNASE2B Antibody, HRP conjugated	ELISA
FITC	CSB-PA841227LC01HU	DNASE2B Antibody, FITC conjugated
Biotin	CSB-PA841227LD01HU	DNASE2B Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.

Gene References into Functions

HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
gene lie head-to-head with the urate oxidase gene PMID: 11700027

Subcellular Location

Lysosome.

Protein Families

DNase II family

Tissue Specificity

Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.

Database Links

HGNC: 28875

OMIM: 608057

KEGG: hsa:58511

STRING: 9606.ENSP00000359699

UniGene: Hs.129142

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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