DR1 Antibody

1. results suggest that DR1 are expressed in the osteosarcoma cells and inhibit the proliferation of osteosarcoma cells by the down-regulation of the ERK1/2 and PI3K-Akt pathways. PMID: 28181134
2. Knockdown of DR1 resulted in reductions of viral RNA and protein production, demonstrating that DR1 acts as a positive host factor in influenza A virus replication. PMID: 25589657
3. Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells. PMID: 20230619
4. The physiological functions of human Dr1 include regulation of polymerase III transcription. PMID: 19965767
5. NC2 controls TBP binding and maintenance on DNA that is largely independent of a canonical TATA sequence PMID: 15574413
6. the initiator core promoter element antagonizes repression of TATA-directed transcription by negative cofactor NC2 PMID: 17584739
7. Data show that NC2beta is specifically involved in neuroblastoma pathogenesis and may be considered a new neuroblastoma biomarker. PMID: 18538002
8. ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein PMID: 18838386
9. heterodimerization with NC2alpha masks the nuclear localization signal in NC2beta, which prevents nuclear export of the NC2 complex PMID: 19204005

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HGNC: 3017

OMIM: 601482

KEGG: hsa:1810

STRING: 9606.ENSP00000359290

UniGene: Hs.348418