DTX2 Antibody

Code CSB-PA007222GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. Q86UW9
Immunogen Human DTX2
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,IHC
Storage Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity purified
Isotype IgG
Alias deltex homolog 2 (Drosophila);DTX2;KIAA1528;MGC71098;RNF58 ;
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Target Names DTX2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
HGNC 15973
RGD 1561790
MGI 1921448
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Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Subcellular Location Cytoplasm, Nucleus
Protein Families Deltex family
Database Links

HGNC: 15973

OMIM: 613141

KEGG: hsa:113878

STRING: 9606.ENSP00000322885

UniGene: Hs.187058

Pathway Notch signaling pathway

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