EFNA2 Antibody

1. Ephrin-A2 expression was correlated with Ki-67 expression in PCa patients, both at the gene scale and protein level. Our data indicate that Ephrin-A2 is a potential diagnostic and prognostic biomarker and a promising molecular therapeutic target to attenuate prostate cancer progression PMID: 26561474
2. these studies suggested that Kaposi's sarcoma-associated herpesvirus utilizes CIB1 as one of the key molecule(s) to coordinate and sustain the EphA2 mediated signaling involved in its entry PMID: 24550731
3. High EphA2 receptor expression in colorectal cancer was associated with a worse outcome in patients treated with cetuximab-based therapy PMID: 24050852
4. Implicate EphA2 as a novel proinflammatory mediator and potential regulator of atherosclerotic plaque development. PMID: 22247258
5. Optic nerve section in adult rat differentially regulates the expression of ephrin-A2 in the superior colliculus(SC).At 1 month, levels were upregulated across the contralateral SC giving rise to an increasing rostro-caudal gradient. PMID: 11860487
6. Different forms of Elf-1 are the products of posttranslational modifications that determine its subcellular localization, activity, and metabolic degradation. PMID: 11884456
7. Abnormal posttranslational mechanisms of the Elf-1 protein result in defective expression of the functional 98-kDa form of Elf-1, and consequently, the transcriptional defect of TCR zeta-chain in patients with systemic lupus erythematosus. PMID: 12421992
8. There is a significant loss of ELF-1 and reduced Smad4 expression in gastrointestinal neoplasms. PMID: 16158060
9. Elf-1 represents the first transcription factor identified to be involved in the transcriptional regulation of Fc receptor gamma PMID: 17878388

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HGNC: 3222

OMIM: 602756

KEGG: hsa:1943

STRING: 9606.ENSP00000215368

UniGene: Hs.741510