EFS Antibody

Code CSB-PA007470GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
EFS
Alternative Names
EFS antibody; CASS3Embryonal Fyn-associated substrate antibody; hEFS antibody; Cas scaffolding protein family member 3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human EFS
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
Gene References into Functions
  1. EFS and CASS4 protein function in the context of the larger CAS family group. [Review] PMID: 26119091
  2. we suggest that EFS should be considered as a novel tumor suppressor gene in prostate cancer. PMID: 25296736
  3. Analysis of 16 Uveal melanoma showed full methylation of the EFS CpG island in 8 (50%), no methylation in 5(31%)and partial methylation in 3 (19%)tumors. Kaplan-Meier analysis revealed higher risk of metastatic progression for tumors with EFS methylation. PMID: 21871071
Protein Families
CAS family
Tissue Specificity
The protein has been detected in lung and placenta.
Database Links

HGNC: 16898

OMIM: 609906

KEGG: hsa:10278

STRING: 9606.ENSP00000216733

UniGene: Hs.24587

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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