EHD1 Antibody

1. Results suggest that EHD1 is a cisplatin (CDDP)-resistant gene that suppresses DNA adduct-induced apoptosis by modulating intracellular CDDP concentrations. PMID: 27411790
2. this study shows that overexpression of EHD1 induced the epithelial-mesenchymal transition and increased the metastatic potential of lung cancer cells in vitro and in vivo PMID: 27531895
3. RAB11FIP3 combines with Eps15 homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor. PMID: 28215104
4. van der Waals interactions should be the main consideration when we design peptide inhibitors of EHD1 EH domain with high affinities. PMID: 26465136
5. Authors found that Eps15-homology domain 1 (EHD1), a protein that associates with the endocytic recycling compartment (ERC), colocalizes with active R-Ras in transiently expressed HeLa cells. PMID: 26378252
6. that Molecule Interacting with CasL Like-1 and Eps15 Homology Domain protein 1 differentially influence microtubule dynamics during early and late mitosis PMID: 25287187
7. Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. PMID: 25595798
8. Data indicate that concordant transforming growth factor-beta1 (TGFbeta-1) positive and EH-domain containing 1 (EHD1) negative as a strong favorable prognosis factor in non-small cell lung cancer (NSCLC). PMID: 24946721
9. MICAL-L1-mediated recruitment of EHD1 to Src-containing recycling endosomes is required for the release of Src from the perinuclear endocytic recycling compartment in response to growth factor stimulation. PMID: 24481818
10. evidence that the functions of both EHD1 and EHD4 are primarily in TRE membrane vesiculation, whereas EHD3 is a membrane-tubulating protein. PMID: 24019528
11. the lipid modifier cPLA2alpha and EHD1 are involved in the vesiculation of CD59-containing endosomes PMID: 22456504
12. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function PMID: 22284051
13. EHD1 is involved in the control of CD59 transport from pre-sorting endosomes to the ERC in a PKC-dependent manner PMID: 20961375
14. A new class of cardiac trafficking proteins(EHD1, EHD2, EHD3, EHD4) regulates cardiac membrane protein targeting. PMID: 20489164
15. The results indicate that NPF is the preferred binding motif for the EHD1 EH-domain, but both the DPF and GPF motifs are capable of binding with lower affinity. PMID: 19798736
16. These data implicate MICAL-L1 as an unusual type of Rab effector that regulates endocytic recycling by recruiting and linking EHD1 and Rab8a on membrane tubules. PMID: 19864458
17. A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane PMID: 12032069
18. EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1. PMID: 12121420
19. a novel interacting partner for EHD1, rabenosyn-5, was revealed. PMID: 15020713
20. ATP binding is required for oligomerization of mRme-1/EHD1, which in turn is required for its association with endosomes PMID: 15710626
21. Data support a role for EHD1 in beta1 integrin recycling, and demonstrate a requirement for EHD1 in integrin-mediated downstream functions. PMID: 17284518
22. Rab8a and Myosin Vb colocalize to a tubular network containing EHD1 and EHD3, which does not contain Rab11a. PMID: 17507647
23. Solution structure of the 133 C-terminal residues of EHD1, which includes the EH domain, was solved. PMID: 17899392
24. Results show that EHD1 undergoes serine-phosphorylation, and suggest that EHD1 phosphorylation occurs between early endosomes and the endocytic recycling compartment. PMID: 18661112
25. Data show that EH domain mutant (K483E) that associates exclusively with punctate membranes displayed decreased binding to phosphatidylinositol-4-phosphate and other phosphoinositides. PMID: 19369419

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HGNC: 3242

OMIM: 605888

KEGG: hsa:10938

STRING: 9606.ENSP00000320516

UniGene: Hs.523774