EID3 Antibody

Datasheet

Code	CSB-PA731077
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA731077(EID3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA731077(EID3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8N140

Target Names

EID3

Alternative Names

E1A-like inhibitor of differentiation 3 antibody; EID 3 antibody; EID-1-like inhibitor of differentiation 3 antibody; EID-3 antibody; EID3 antibody; EID3_HUMAN antibody; EP300 interacting inhibitor of differentiation 3 antibody; EP300-interacting inhibitor of differentiation 3 antibody; FLJ25832 antibody; Non-SMC element 4; S. cerevisiae; homolog of; B antibody; Non-structural maintenance of chromosomes element 4 homolog B antibody; NSE4B antibody; NSMCE4B antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human EID3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.; Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.

Gene References into Functions

Knockdown of EID3 by specific shRNA attenuated BMS-345541 -induced radiosensitization in MCF-7 cells. PMID: 30114644
These findings indicated a novel mechanism by which EID3, a p300 acetyltransferase inhibitor, could directly affect DNMT3A, this enzyme possesses dual methylation and demethylation abilities. PMID: 28074931
EID3 acts as an inhibitor of CBP/p300-dependent transcription in a tissue-specific manner. PMID: 15987788

Subcellular Location

Nucleus. Cytoplasm. Chromosome, telomere.

Protein Families

NSE4 family

Tissue Specificity

Highly expressed in testis.

Database Links

HGNC: 32961

OMIM: 612986

KEGG: hsa:493861

STRING: 9606.ENSP00000435619

UniGene: Hs.659857

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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