EIF1 Antibody, FITC conjugated

Code CSB-PA007503LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EIF1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
EIF1 antibody; SUI1Eukaryotic translation initiation factor 1 antibody; eIF1 antibody; A121 antibody; Protein translation factor SUI1 homolog antibody; Sui1iso1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Eukaryotic translation initiation factor 1 protein (2-113AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA.
Gene References into Functions
  1. Anti-Sui1 could be utilized as a supplementary serological marker. PMID: 26386724
  2. eIF1A is a novel component of the Ago2-centred RNA-induced silencing complexes (RISCs) and augments Ago2-dependent RNAi and miRNA biogenesis. PMID: 26018492
  3. eEF4GI shares this activity and also interacts with eIF1. PMID: 25738462
  4. eIF1, eIF1A, eIF3j, and the eIF2-GTP-Met-tRNAi ternary complex stably bind to the 43 S preinitiation complex PMID: 25246524
  5. Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complex PMID: 23293029
  6. This study provides mechanistic insight into the role of eIF5-carboxyl terminal domain's dynamic interplay with eIF1 and eIF2beta. PMID: 22813744
  7. show that the stringency of start codon selection (preferential utilization of optimal start sites) is increased to a surprising degree by overexpressing eIF1 PMID: 20921384

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Protein Families
SUI1 family
Database Links

HGNC: 3249

KEGG: hsa:10209

STRING: 9606.ENSP00000419449

UniGene: Hs.150580

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