ELAVL2 Antibody

Code CSB-PA007593LA01HU
Size US$166
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  • Western blot
    All lanes: ELAVL2 antibody at 2µg/ml + Mouse brain tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 40, 39 kDa
    Observed band size: 40 kDa

  • Immunohistochemistry analysis of human brain tissue using CSB-PA007593LA01HU at dilution of 1:100

  • Immunohistochemistry analysis of human colon cancer using CSB-PA007593LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA007593LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Immunofluorescent analysis of PC-3 cells using CSB-PA007593LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ELAVL2 Polyclonal antibody
Uniprot No.
Target Names
ELAVL2
Alternative Names
ELAV like neuron specific RNA binding protein 2 antibody; ELAV like Neuronal Protein 1 antibody; ELAV like Protein 2 antibody; ELAV-like neuronal protein 1 antibody; ELAV-like protein 2 antibody; ELAV2_HUMAN antibody; ELAVL2 antibody; HEL-N1 antibody; HELN1 antibody; HU Antigen B antibody; Hu-antigen B antibody; HuB antibody; Nervous System Specific RNA Binding Protein MelN1 antibody; Nervous system-specific RNA-binding protein Hel-N1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human ELAV-like protein 2 protein (4-356AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ELAVL2 Antibody (Product code: CSB-PA007593LA01HU) is Non-conjugated. For ELAVL2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007593LB01HU ELAVL2 Antibody, HRP conjugated ELISA
FITC CSB-PA007593LC01HU ELAVL2 Antibody, FITC conjugated
Biotin CSB-PA007593LD01HU ELAVL2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs. Seems to recognize a GAAA motif. Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR.
Gene References into Functions
  1. ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism PMID: 27260404
  2. The 17 proteins that interact with 10 or more other proteins (P < 0.05, FDR < 0.05) were identified as the hub proteins. PMID: 26366417
  3. Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 and ELAVL2 among European mothers PMID: 23512105
  4. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA PMID: 15671036
  5. increased level of mRNA transcripts detected in Small Cell Lung Cancer patients PMID: 18607064

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Protein Families
RRM elav family
Tissue Specificity
Brain; neural-specific.
Database Links

HGNC: 3313

OMIM: 601673

KEGG: hsa:1993

STRING: 9606.ENSP00000369460

UniGene: Hs.166109

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