ELAVL2 Antibody

Datasheet

Code	CSB-PA240124
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA240124(ELAVL2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA240124(ELAVL2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q12926

Target Names

ELAVL2

Alternative Names

ELAV like neuron specific RNA binding protein 2 antibody; ELAV like Neuronal Protein 1 antibody; ELAV like Protein 2 antibody; ELAV-like neuronal protein 1 antibody; ELAV-like protein 2 antibody; ELAV2_HUMAN antibody; ELAVL2 antibody; HEL-N1 antibody; HELN1 antibody; HU Antigen B antibody; Hu-antigen B antibody; HuB antibody; Nervous System Specific RNA Binding Protein MelN1 antibody; Nervous system-specific RNA-binding protein Hel-N1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human ELAVL2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:10000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs. Seems to recognize a GAAA motif. Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR.

Gene References into Functions

ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism PMID: 27260404
The 17 proteins that interact with 10 or more other proteins (P < 0.05, FDR < 0.05) were identified as the hub proteins. PMID: 26366417
Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 and ELAVL2 among European mothers PMID: 23512105
the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA PMID: 15671036
increased level of mRNA transcripts detected in Small Cell Lung Cancer patients PMID: 18607064

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Protein Families

RRM elav family

Tissue Specificity

Brain; neural-specific.

Database Links

HGNC: 3313

OMIM: 601673

KEGG: hsa:1993

STRING: 9606.ENSP00000369460

UniGene: Hs.166109

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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