ELP2 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA740224LD01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ELP2 Polyclonal antibody

Uniprot No.

Q6IA86

Target Names

ELP2

Alternative Names

AU023723 antibody; Elongation protein 2 homolog (S. cerevisiae) antibody; Elongator acetyltransferase complex subunit 2 antibody; Elongator complex protein 2 antibody; elongator protein 2 antibody; ELP2 antibody; ELP2_HUMAN antibody; Epl2 antibody; FLJ10879 antibody; SHINC 2 antibody; SHINC-2 antibody; SHINC2 antibody; signal transducer and activator of transcription 3 interacting protein 1 antibody; signal transducer and activator of transcription interacting protein 1 antibody; STAT3 interacting protein 1 antibody; Stat3 interacting protein antibody; STAT3-interacting protein 1 antibody; STATIP 1 antibody; STATIP1 antibody; STATIP1 protein antibody; StIP antibody; StIP1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Elongator complex protein 2 protein (323-457AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

Gene References into Functions

ELP2 mutation is implicated in severe intellectual disability, spastic diplegia, and self-injurious behavior described in two brothers. PMID: 25847581
Studied the possible relationship between STATIP1, STAT3 and CML resistance. PMID: 25417721
Elp2 and STAT-3 mediate, at least in part, the stimulation of Hsp70 expression by 4PBA. PMID: 22069317

Involvement in disease

Mental retardation, autosomal recessive 58 (MRT58)

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

WD repeat ELP2 family

Database Links

HGNC: 18248

OMIM: 616054

KEGG: hsa:55250

UniGene: Hs.606040

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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