ELP2 Antibody

Code CSB-PA004186
Size US$100
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  • Western Blot analysis of HT29 cells using StIp1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ELP2
Alternative Names
AU023723 antibody; Elongation protein 2 homolog (S. cerevisiae) antibody; Elongator acetyltransferase complex subunit 2 antibody; Elongator complex protein 2 antibody; elongator protein 2 antibody; ELP2 antibody; ELP2_HUMAN antibody; Epl2 antibody; FLJ10879 antibody; SHINC 2 antibody; SHINC-2 antibody; SHINC2 antibody; signal transducer and activator of transcription 3 interacting protein 1 antibody; signal transducer and activator of transcription interacting protein 1 antibody; STAT3 interacting protein 1 antibody; Stat3 interacting protein antibody; STAT3-interacting protein 1 antibody; STATIP 1 antibody; STATIP1 antibody; STATIP1 protein antibody; StIP antibody; StIP1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human StIp1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Gene References into Functions
  1. ELP2 mutation is implicated in severe intellectual disability, spastic diplegia, and self-injurious behavior described in two brothers. PMID: 25847581
  2. Studied the possible relationship between STATIP1, STAT3 and CML resistance. PMID: 25417721
  3. Elp2 and STAT-3 mediate, at least in part, the stimulation of Hsp70 expression by 4PBA. PMID: 22069317
Involvement in disease
Mental retardation, autosomal recessive 58 (MRT58)
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
WD repeat ELP2 family
Database Links

HGNC: 18248

OMIM: 616054

KEGG: hsa:55250

UniGene: Hs.606040

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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