ELP2 Antibody, HRP conjugated

Code CSB-PA740224LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ELP2 Polyclonal antibody
Uniprot No.
Target Names
ELP2
Alternative Names
AU023723 antibody; Elongation protein 2 homolog (S. cerevisiae) antibody; Elongator acetyltransferase complex subunit 2 antibody; Elongator complex protein 2 antibody; elongator protein 2 antibody; ELP2 antibody; ELP2_HUMAN antibody; Epl2 antibody; FLJ10879 antibody; SHINC 2 antibody; SHINC-2 antibody; SHINC2 antibody; signal transducer and activator of transcription 3 interacting protein 1 antibody; signal transducer and activator of transcription interacting protein 1 antibody; STAT3 interacting protein 1 antibody; Stat3 interacting protein antibody; STAT3-interacting protein 1 antibody; STATIP 1 antibody; STATIP1 antibody; STATIP1 protein antibody; StIP antibody; StIP1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Elongator complex protein 2 protein (323-457AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Gene References into Functions
  1. ELP2 mutation is implicated in severe intellectual disability, spastic diplegia, and self-injurious behavior described in two brothers. PMID: 25847581
  2. Studied the possible relationship between STATIP1, STAT3 and CML resistance. PMID: 25417721
  3. Elp2 and STAT-3 mediate, at least in part, the stimulation of Hsp70 expression by 4PBA. PMID: 22069317
Involvement in disease
Mental retardation, autosomal recessive 58 (MRT58)
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
WD repeat ELP2 family
Database Links

HGNC: 18248

OMIM: 616054

KEGG: hsa:55250

UniGene: Hs.606040

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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