ENOX1 Antibody, HRP conjugated

Code CSB-PA007676LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ENOX1 Polyclonal antibody
Uniprot No.
Target Names
ENOX1
Alternative Names
ENOX1 antibody; PIG38Ecto-NOX disulfide-thiol exchanger 1 antibody; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase antibody; cCNOX antibody; Cell proliferation-inducing gene 38 protein antibody; Constitutive Ecto-NOX antibody; cNOX) [Includes: Hydroquinone [NADH] oxidase antibody; EC 1.-.-.-); Protein disulfide-thiol oxidoreductase antibody; EC 1.-.-.-)] antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ecto-NOX disulfide-thiol exchanger 1 protein (101-340AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.
Gene References into Functions
  1. We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons. PMID: 23939472
  2. These results indicate that this sequence variant in ENOX1 may contribute to the familial autoimmune myasthenia in these patients. PMID: 22744667
  3. copper-binding capacity, enzymatic activity, and time-keeping (clock) properties PMID: 19055324
Subcellular Location
Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
Protein Families
ENOX family
Tissue Specificity
Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of heal
Database Links

HGNC: 25474

OMIM: 610914

KEGG: hsa:55068

STRING: 9606.ENSP00000261488

UniGene: Hs.128258

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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