EPN3 Antibody

Datasheet

Code	CSB-PA867130LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA867130LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA867130LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA867130LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) EPN3 Polyclonal antibody

Uniprot No.

Q9H201

Target Names

EPN3

Alternative Names

EPN 3 antibody; Epn3 antibody; EPN3_HUMAN antibody; EPS 15 interacting protein 3 antibody; EPS-15-interacting protein 3 antibody; Epsin 3 antibody; Epsin-3 antibody; Epsin3 antibody; FLJ20778 antibody; MGC129899 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Epsin-3 protein (25-208AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The EPN3 Antibody (Product code: CSB-PA867130LA01HU) is Non-conjugated. For EPN3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA867130LB01HU	EPN3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA867130LC01HU	EPN3 Antibody, FITC conjugated
Biotin	CSB-PA867130LD01HU	EPN3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Gene References into Functions

These results suggested that EPN3 enhances the migration and invasion of glioblastoma cells by activating the transcription factors Slug, Twist and ZEB1, but not Snail 1 or ZEB2, to induce EMT in glioma cells; EPN3 involvement in the Notch and WNT/betacatenin signaling pathways may contribute to this process. PMID: 30226603
High expression of epsin (EPN3) was associated with increased risk of late metastasis. PMID: 27926932

Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.

Protein Families

Epsin family

Tissue Specificity

Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

Database Links

HGNC: 18235

OMIM: 607264

KEGG: hsa:55040

STRING: 9606.ENSP00000268933

UniGene: Hs.670090

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Endocytosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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