EPN3 Antibody, HRP conjugated

Code CSB-PA867130LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EPN3 Polyclonal antibody
Uniprot No.
Target Names
EPN3
Alternative Names
EPN 3 antibody; Epn3 antibody; EPN3_HUMAN antibody; EPS 15 interacting protein 3 antibody; EPS-15-interacting protein 3 antibody; Epsin 3 antibody; Epsin-3 antibody; Epsin3 antibody; FLJ20778 antibody; MGC129899 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Epsin-3 protein (25-208AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. These results suggested that EPN3 enhances the migration and invasion of glioblastoma cells by activating the transcription factors Slug, Twist and ZEB1, but not Snail 1 or ZEB2, to induce EMT in glioma cells; EPN3 involvement in the Notch and WNT/betacatenin signaling pathways may contribute to this process. PMID: 30226603
  2. High expression of epsin (EPN3) was associated with increased risk of late metastasis. PMID: 27926932
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
Protein Families
Epsin family
Tissue Specificity
Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
Database Links

HGNC: 18235

OMIM: 607264

KEGG: hsa:55040

STRING: 9606.ENSP00000268933

UniGene: Hs.670090

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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