FAM83D Antibody, FITC conjugated

Datasheet
Code CSB-PA887979LC01HU
Size US$299
Uniprot No. Q9H4H8
Protocols ELISA Protocol
Immunogen Recombinant Human Protein FAM83D protein (339-470AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Protein FAM83D (Spindle protein CHICA), FAM83D, C20orf129
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names FAM83D
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC
Subcellular Location Cytoplasm, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole
Protein Families FAM83 family
Database Links

HGNC: 16122

KEGG: hsa:81610

STRING: 9606.ENSP00000217429

UniGene: Hs.726442

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