FARP1 Antibody, FITC conjugated

Code CSB-PA897492LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FARP1 Polyclonal antibody
Uniprot No.
Target Names
FARP1
Alternative Names
CDEP antibody; Chondrocyte derived ezrin like protein antibody; Chondrocyte-derived ezrin-like protein antibody; FARP1 antibody; FARP1_HUMAN antibody; FERM RhoGEF and pleckstrin domain containing protein 1 antibody; FERM antibody; FERM RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) antibody; FERM; ARHGEF; and pleckstrin domain protein 1 antibody; PH domain-containing family C member 2 antibody; Pleckstrin homology domain-containing family C member 2 antibody; PLEKHC2 antibody; PPP1R75 antibody; protein phosphatase 1; regulatory subunit 75 antibody; RhoGEF and pleckstrin domain-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 1 protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses.
Gene References into Functions
  1. We have reported here for the first time a reduced activity of both Rac1 and Cdc42 in human pheochromocytoma resection as well as tumor-associated expression changes of FARP1, ARHGEF1, and ARHGAP36 PMID: 26911374
Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell junction, synapse, synaptosome. Cytoplasm, cytosol. Cell projection, filopodium. Cell projection, dendrite. Cell projection, dendritic spine.
Tissue Specificity
Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung.
Database Links

HGNC: 3591

OMIM: 602654

KEGG: hsa:10160

STRING: 9606.ENSP00000322926

UniGene: Hs.403917

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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