FGF16 Antibody

Datasheet

Code	CSB-PA008621LA01HU
Size	US$166
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Image	IHC image of CSB-PA008621LA01HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FGF16 Polyclonal antibody

Uniprot No.

O43320

Target Names

FGF16

Alternative Names

FGF 16 antibody; FGF-16 antibody; Fgf16 antibody; FGF16_HUMAN antibody; Fibroblast growth factor 16 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Fibroblast growth factor 16 protein (1-207AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The FGF16 Antibody (Product code: CSB-PA008621LA01HU) is Non-conjugated. For FGF16 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA008621LB01HU	FGF16 Antibody, HRP conjugated	ELISA
FITC	CSB-PA008621LC01HU	FGF16 Antibody, FITC conjugated
Biotin	CSB-PA008621LD01HU	FGF16 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.

Gene References into Functions

Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID: 28409700
Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID: 24878828
impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID: 24706454
Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID: 20097674
HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID: 16756958

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Involvement in disease

Metacarpal 4-5 fusion (MF4)

Subcellular Location

Secreted.

Protein Families

Heparin-binding growth factors family

Database Links

HGNC: 3672

OMIM: 300827

KEGG: hsa:8823

STRING: 9606.ENSP00000399324

UniGene: Hs.666364

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Service

Phage Display Service

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Protein Service

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Oligo Synthesis Service

The Overview of One Category of Important Cell Receptors: Receptor Tyrosine Kinases The Overview of Growth Factor Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

MAPK signaling pathway PI3K-Akt signaling pathway Regulation of actin cytoskeleton Ras signaling pathway Rap1 signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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