FGF16 Antibody

Code CSB-PA005775
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
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  • Western Blot analysis of K562 cells using FGF-16 Polyclonal Antibody.
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Product Details

Uniprot No. O43320
Target Names FGF16
Alternative Names FGF 16 antibody; FGF-16 antibody; Fgf16 antibody; FGF16_HUMAN antibody; Fibroblast growth factor 16 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of Human FGF-16.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
Gene References into Functions
  1. Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID: 28409700
  2. Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID: 24878828
  3. impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID: 24706454
  4. Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID: 20097674
  5. HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID: 16756958

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Involvement in disease Metacarpal 4-5 fusion (MF4)
Subcellular Location Secreted.
Protein Families Heparin-binding growth factors family
Database Links

HGNC: 3672

OMIM: 300827

KEGG: hsa:8823

STRING: 9606.ENSP00000399324

UniGene: Hs.666364

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