FGL1 Antibody

Code CSB-PA008653LA01HU
Size US$166
Order now
Image
  • Western Blot
    Positive WB detected in: K562 whole cell lysate
    All lanes: FGL1 antibody at 5.8µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 37 kDa
    Observed band size: 37 kDa

  • IHC image of CSB-PA008653LA01HU diluted at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FGL1 Polyclonal antibody
Uniprot No.
Target Names
FGL1
Alternative Names
FGL 1 antibody; Fgl1 antibody; FGL1_HUMAN antibody; Fibrinogen like 1 antibody; Fibrinogen like protein 1 antibody; Fibrinogen related protein 1 antibody; Fibrinogen-like protein 1 antibody; Hepassocin antibody; Hepatocellular carcinoma related sequence antibody; Hepatocyte derived fibrinogen related protein 1 antibody; Hepatocyte-derived fibrinogen-related protein 1 antibody; HFREP 1 antibody; HFREP-1 antibody; HFREP1 antibody; HP 041 antibody; HP-041 antibody; HP041 antibody; LFIRE 1 antibody; LFIRE-1 antibody; LFIRE1 antibody; Liver fibrinogen related protein 1 antibody; Liver fibrinogen-related protein 1 antibody; MFIRE 1 antibody; MGC108569 antibody; MGC12455 antibody; MGC37822 antibody; OTTHUMP00000122468 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Fibrinogen-like protein 1 protein (179-282AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The FGL1 Antibody (Product code: CSB-PA008653LA01HU) is Non-conjugated. For FGL1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA008653LB01HU FGL1 Antibody, HRP conjugated ELISA
FITC CSB-PA008653LC01HU FGL1 Antibody, FITC conjugated
Biotin CSB-PA008653LD01HU FGL1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes.
Gene References into Functions
  1. FGL1 promotes invasion and metastasis of gastric cancer and is associated with poor prognosis. PMID: 29845203
  2. findings highlight the crucial role of HFREP1 in insulin resistance and diabetes, and provide a potential strategy and biomarker for developing therapeutic approaches to combat these diseases. PMID: 27221093
  3. Hepassocin plays an important role in non-alcoholic fatty liver disease and induces hepatic lipid accumulation through an ERK1/2-dependent pathway. PMID: 23792031
  4. Here, the application of small ubiquitin-related modifier (SUMO) fusion technology in combination with four different chaperone teams on the soluble expression of recombinant HPS protein was explored and analyzed. PMID: 24084006
  5. Findings suggest that hepassocin promotes hepatic cell line L02 cells proliferation via an autocrine mechanism and inhibits HCC cells proliferation by an intracrine pathway. PMID: 21618590
  6. data demonstrated that liver-specific gene LFIRE-1/HFREP-1 was frequently downregulated and might possess growth suppressor activity in HCC PMID: 14981537
  7. HFREP-1 in plasma almost completely bound to the fibrin matrix during clot formation PMID: 16996032
  8. The enhancement of FGL1 levels in vitro by IL-6 and its induction after turpentine oil injection suggest that it is an acute phase reactant. PMID: 18039467
  9. HNF1 binding site and HNF1alpha are critical to liver-specific expression of HPS, and down-regulation or loss of HNF1alpha causes, at least in part, the transcriptional down-regulation of HPS in HCC. PMID: 19304666

Show More

Hide All

Subcellular Location
Secreted.
Tissue Specificity
Under normal conditions, liver-specific.
Database Links

HGNC: 3695

OMIM: 605776

KEGG: hsa:2267

STRING: 9606.ENSP00000221204

UniGene: Hs.491143

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*