FMN1 Antibody, Biotin conjugated

Code CSB-PA715012LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FMN1 Polyclonal antibody
Uniprot No.
Target Names
FMN1
Alternative Names
FMN1 antibody; FMN antibody; LDFormin-1 antibody; Limb deformity protein homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Formin-1 protein (354-487AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
Gene References into Functions
  1. Formin-1 (FMN1) was shown to reside in the nucleus and studies indicate that some formins can shuttle in and out of the nucleus. PMID: 27913680
  2. actin arcs populating the medial, lamella-like region of the immunological synapse (IS) arise from linear actin filaments generated by one or more formins present at the IS distal edge. PMID: 27799367
  3. Filopodia initiation: focus on the Arp2/3 complex and formins. PMID: 21975549
  4. Chromosomal imbalances in the GREM1 FMN1 region in individuals with limb defects are reported here. PMID: 20610440
  5. The obtained data indicate the possibility of participation of polymorphism in gene FMN1 in formation of predisposition to prostate cancer. PMID: 20540360
  6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  7. Observational study of gene-disease association. (HuGE Navigator) PMID: 20540360
  8. Observational study of gene-disease association. (HuGE Navigator) PMID: 20200978
  9. both mammalian Spir proteins, Spir-1 and Spir-2, interact with mammalian Fmn subgroup proteins formin-1 and formin-2 PMID: 19605360
  10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19096130

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Subcellular Location
Nucleus. Cytoplasm. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
Formin homology family, Cappuccino subfamily
Database Links

HGNC: 3768

OMIM: 136535

KEGG: hsa:342184

STRING: 9606.ENSP00000333950

UniGene: Hs.657649

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