FMN1 Antibody, FITC conjugated

Code CSB-PA715012LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FMN1 Polyclonal antibody
Uniprot No.
Target Names
FMN1
Alternative Names
FMN1 antibody; FMN antibody; LDFormin-1 antibody; Limb deformity protein homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Formin-1 protein (354-487AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
Gene References into Functions
  1. Formin-1 (FMN1) was shown to reside in the nucleus and studies indicate that some formins can shuttle in and out of the nucleus. PMID: 27913680
  2. actin arcs populating the medial, lamella-like region of the immunological synapse (IS) arise from linear actin filaments generated by one or more formins present at the IS distal edge. PMID: 27799367
  3. Filopodia initiation: focus on the Arp2/3 complex and formins. PMID: 21975549
  4. Chromosomal imbalances in the GREM1 FMN1 region in individuals with limb defects are reported here. PMID: 20610440
  5. The obtained data indicate the possibility of participation of polymorphism in gene FMN1 in formation of predisposition to prostate cancer. PMID: 20540360
  6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  7. Observational study of gene-disease association. (HuGE Navigator) PMID: 20540360
  8. Observational study of gene-disease association. (HuGE Navigator) PMID: 20200978
  9. both mammalian Spir proteins, Spir-1 and Spir-2, interact with mammalian Fmn subgroup proteins formin-1 and formin-2 PMID: 19605360
  10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19096130

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Subcellular Location
Nucleus. Cytoplasm. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
Formin homology family, Cappuccino subfamily
Database Links

HGNC: 3768

OMIM: 136535

KEGG: hsa:342184

STRING: 9606.ENSP00000333950

UniGene: Hs.657649

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