FRMD5 Antibody

Code CSB-PA773602LA01HU
Size US$166
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Image
  • Western blot
    All lanes: FRMD5 antibody at 16 μg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse heart tissue
    Lane 3: Mouse skeletal muscle tissue
    Lane 4: Mouse lung tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 66, 64 kDa
    Observed band size: 65 kDa

  • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA773602LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA773602LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA773602LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FRMD5 Polyclonal antibody
Uniprot No.
Target Names
FRMD5
Alternative Names
FRMD5; FERM domain-containing protein 5
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human FERM domain-containing protein 5 protein (295-504AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The FRMD5 Antibody (Product code: CSB-PA773602LA01HU) is Non-conjugated. For FRMD5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA773602LB01HU FRMD5 Antibody, HRP conjugated ELISA
FITC CSB-PA773602LC01HU FRMD5 Antibody, FITC conjugated
Biotin CSB-PA773602LD01HU FRMD5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation.
Gene References into Functions
  1. We conclude that integrative variants, haplotypes and diplotypes of the CAPN3 rs4344713 and FRMD5 rs524908, as well as DBP and BMI are associated with serum lipid variables in the Jing and Han populations. PMID: 28332615
  2. Data show that FERM domain-containing protein 5 (FRMD5) is regulated by both beta-catenin and transcription factor 7-Like 2 protein (TCF7L2) in colon cancer cells. PMID: 28117551
  3. FRMD5 regulates tumor cell motility via a dual pathway involving FRMD5 binding to integrin beta5 tail and to ROCK1 PMID: 25448675
  4. FRMD5 may play a role in p120-catenin-based cell-cell contact and is involved in the regulation of tumor progression PMID: 22846708
Subcellular Location
Membrane; Single-pass membrane protein. Cell junction, adherens junction.
Database Links

HGNC: 28214

OMIM: 616309

KEGG: hsa:84978

STRING: 9606.ENSP00000403067

UniGene: Hs.578544

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