FUZ Antibody, Biotin conjugated

Code CSB-PA883593LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FUZ Polyclonal antibody
Uniprot No.
Target Names
FUZ
Alternative Names
FLJ22688 antibody; fuz antibody; FUZZY_HUMAN antibody; Fy antibody; Protein fuzzy homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein fuzzy homolog protein (280-404AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.
Gene References into Functions
  1. results in vitro show that FUZ is responsible for non-small-cell lung cancer (NSCLC) progression and metastasis, suggesting that FUZ can be a potential therapeutic target for NSCLC. PMID: 29421438
  2. Data propose that mutations in Fuzzy may account for a subset of neural tube defects in humans. PMID: 21840926
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body.
Protein Families
Fuzzy family
Database Links

HGNC: 26219

OMIM: 610622

KEGG: hsa:80199

STRING: 9606.ENSP00000313309

UniGene: Hs.288800

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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