GLIPR2 Antibody

Datasheet

Code	CSB-PA880974LA01HU
Size	US$166
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Image	IHC image of CSB-PA880974LA01HU diluted at 1:600 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GLIPR2 Polyclonal antibody

Uniprot No.

Q9H4G4

Target Names

GLIPR2

Alternative Names

5730414A08Rik antibody; C77180 antibody; C9orf19 antibody; GAPR 1 antibody; GAPR-1 antibody; GAPR1_HUMAN antibody; GLI pathogenesis related 2 antibody; Glioma pathogenesis related protein 2 antibody; Glioma pathogenesis-related protein 2 antibody; GliPR 2 antibody; GLIPR2 antibody; Golgi associated plant pathogenesis related protein 1 antibody; Golgi associated PR 1 protein antibody; Golgi-associated plant pathogenesis-related protein 1 antibody; Golgi-associated PR-1 protein antibody; OTTMUSP00000007558 antibody; RP11-421H8.5 antibody; RP23-209M8.2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Golgi-associated plant pathogenesis-related protein 1 protein (2-85AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GLIPR2 Antibody (Product code: CSB-PA880974LA01HU) is Non-conjugated. For GLIPR2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA880974LB01HU	GLIPR2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA880974LC01HU	GLIPR2 Antibody, FITC conjugated
Biotin	CSB-PA880974LD01HU	GLIPR2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:500-1:1000

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1. PMID: 28876241
This study identified a previously unrecognized role for GAPR-1 to control a unifying TLR4 signaling complex and to regulate type I Interferon signaling activation. PMID: 26678074
Hypoxia promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells via inducing GLIPR-2 expression. PMID: 24204846
GLIPR-2 overexpression in HK-2 cells can potentiate EMT-like processes in this cell type through the ERK1/2 signaling pathway PMID: 23516513
the charge properties of the lipid bilayer can regulate GAPR-1 dynamics as a potential mechanism to modulate GAPR-1 function PMID: 22560898

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Subcellular Location

Golgi apparatus membrane; Lipid-anchor. Note=Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.

Protein Families

CRISP family

Tissue Specificity

Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney.

Database Links

HGNC: 18007

OMIM: 607141

KEGG: hsa:152007

STRING: 9606.ENSP00000367196

UniGene: Hs.493819

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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