GLIPR2 Antibody, Biotin conjugated

Code CSB-PA880974LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GLIPR2 Polyclonal antibody
Uniprot No.
Target Names
GLIPR2
Alternative Names
5730414A08Rik antibody; C77180 antibody; C9orf19 antibody; GAPR 1 antibody; GAPR-1 antibody; GAPR1_HUMAN antibody; GLI pathogenesis related 2 antibody; Glioma pathogenesis related protein 2 antibody; Glioma pathogenesis-related protein 2 antibody; GliPR 2 antibody; GLIPR2 antibody; Golgi associated plant pathogenesis related protein 1 antibody; Golgi associated PR 1 protein antibody; Golgi-associated plant pathogenesis-related protein 1 antibody; Golgi-associated PR-1 protein antibody; OTTMUSP00000007558 antibody; RP11-421H8.5 antibody; RP23-209M8.2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Golgi-associated plant pathogenesis-related protein 1 protein (2-85AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1. PMID: 28876241
  2. This study identified a previously unrecognized role for GAPR-1 to control a unifying TLR4 signaling complex and to regulate type I Interferon signaling activation. PMID: 26678074
  3. Hypoxia promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells via inducing GLIPR-2 expression. PMID: 24204846
  4. GLIPR-2 overexpression in HK-2 cells can potentiate EMT-like processes in this cell type through the ERK1/2 signaling pathway PMID: 23516513
  5. the charge properties of the lipid bilayer can regulate GAPR-1 dynamics as a potential mechanism to modulate GAPR-1 function PMID: 22560898

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Subcellular Location
Golgi apparatus membrane; Lipid-anchor. Note=Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.
Protein Families
CRISP family
Tissue Specificity
Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney.
Database Links

HGNC: 18007

OMIM: 607141

KEGG: hsa:152007

STRING: 9606.ENSP00000367196

UniGene: Hs.493819

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