GLIPR2 Antibody, FITC conjugated

1. Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1. PMID: 28876241
2. This study identified a previously unrecognized role for GAPR-1 to control a unifying TLR4 signaling complex and to regulate type I Interferon signaling activation. PMID: 26678074
3. Hypoxia promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells via inducing GLIPR-2 expression. PMID: 24204846
4. GLIPR-2 overexpression in HK-2 cells can potentiate EMT-like processes in this cell type through the ERK1/2 signaling pathway PMID: 23516513
5. the charge properties of the lipid bilayer can regulate GAPR-1 dynamics as a potential mechanism to modulate GAPR-1 function PMID: 22560898

Show More

Hide All

HGNC: 18007

OMIM: 607141

KEGG: hsa:152007

STRING: 9606.ENSP00000367196

UniGene: Hs.493819