GPR133 Antibody

Code CSB-PA008902
Size US$100
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Product Details

Uniprot No.
Target Names
ADGRD1
Alternative Names
DKFZp434B1272 antibody; FLJ16770 antibody; G protein coupled receptor 133 antibody; G protein coupled receptor PGR25 antibody; G-protein coupled receptor PGR25 antibody; GP133_HUMAN antibody; Gpr133 antibody; MGC138512 antibody; MGC138514 antibody; PGR25 antibody; Probable G-protein coupled receptor 133 antibody
Raised in
Rabbit
Species Reactivity
Human,Monkey
Immunogen
Synthesized peptide derived from the Internal region of Human GPR133.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews
Average Rating:
5.0 - 1 reviews

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Applications : Western Blot (WB)

Sample type: cell

Sample dilution: 1:1000

Review: I used a CSB-PA008902 antibody to detect the expression of GPR133 protein in my cells, and I used 37°C, 30min to denatured the protein because it is a membrane protein. The sample load was 15 ug of total protein, the bands were clear, and the results were not bad.

By Anonymous

Target Background

Function
Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma.
Gene References into Functions
  1. The results show that a broad spectrum of functionally relevant ADGRD1 variants is present in the human population which may cause clinically relevant phenotypes, while being compatible with life when heterozygous. PMID: 27516204
  2. Cell adhesion receptor GPR133 couples to Gs protein PMID: 22025619
  3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  4. A role for GPR133 protein in affecting the length of the electrocardiographic RR interval and heart rate. PMID: 20031603
  5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20031603
  6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19729412

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity
Up-regulated in CD133(+) cell population of glioblastoma.
Database Links

HGNC: 19893

OMIM: 613639

KEGG: hsa:283383

STRING: 9606.ENSP00000261654

UniGene: Hs.719239

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