GPR3 Antibody

Code CSB-PA209020
Size US$166
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  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human ovarian cancer tissue, Primary antibody: CSB-PA209020(GPR3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Product Details

Uniprot No.
Target Names
Alternative Names
GPR3; ACCA; G-protein coupled receptor 3; ACCA orphan receptor
Raised in
Species Reactivity
Synthetic peptide of Human GPR3
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen affinity purification
It differs from different batches. Please contact us to confirm it.
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Tested Applications
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
WB 1:200-1:1000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress, amyloid-beta peptide generation in neurons and neurite outgrowth. Maintains also meiotic arrest in oocytes.
Gene References into Functions
  1. Results demonstrate that GPR3 signals at the plasma membrane and can be silenced by GRK2/beta-arrestin overexpression. These results also strongly implicate the serine and/or threonine residues in the third intracellular loop in the regulation of GPR3 activity. PMID: 23826079
  2. Gpr3 stimulates Abeta production via interactions with APP and beta-arrestin2. PMID: 24069330
  3. GPR3 is a key factor in the regulation of the nervous system and follicle development.[review] PMID: 23732663
  4. GPR3 is expressed in the ovary and testes, and is necessary for the regulation of meiosis in mouse. PMID: 15591206
  5. Mutations in GPR3 are not a common cause of premature ovarian failure in Chinese women. PMID: 20158988
  6. control of gene expression in vascular endothelial cells in the presence of fluid shear stress and classifies it as a sphingosine 1-phosphate receptor. PMID: 12649592
  7. We conclude that perturbations in GPR3 are not a common explanation for POF in this population. PMID: 17953967

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease.
Database Links

HGNC: 4484

OMIM: 600241

KEGG: hsa:2827

STRING: 9606.ENSP00000363136

UniGene: Hs.66542

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