GTPBP1 Antibody

Datasheet

Code	CSB-PA010031LA01HU
Size	US$166
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Image	IHC image of CSB-PA010031LA01HU diluted at 1:500 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. Immunofluorescence staining of 293 cells with CSB-PA010031LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GTPBP1 Polyclonal antibody

Uniprot No.

O00178

Target Names

GTPBP1

Alternative Names

G protein 1 antibody; G-protein 1 antibody; GP 1 antibody; GP-1 antibody; GP1 antibody; GTP binding protein 1 antibody; GTP-binding protein 1 antibody; GTPB1_HUMAN antibody; GTPBP1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human GTP-binding protein 1 protein (562-669AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GTPBP1 Antibody (Product code: CSB-PA010031LA01HU) is Non-conjugated. For GTPBP1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA010031LB01HU	GTPBP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA010031LC01HU	GTPBP1 Antibody, FITC conjugated
Biotin	CSB-PA010031LD01HU	GTPBP1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:500-1:1000
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

Gene References into Functions

GTPBP1 possesses eEF1A-like elongation activity, delivering cognate aminoacyl-transfer RNA to the ribosomal A site in a GTP-dependent manner. It also stimulates exosomal degradation of mRNAs in elongation complexes. PMID: 30108131

Subcellular Location

Cytoplasm.

Protein Families

TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, GTPBP1 subfamily

Database Links

HGNC: 4669

OMIM: 602245

KEGG: hsa:9567

STRING: 9606.ENSP00000216044

UniGene: Hs.276925

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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