GTPBP1 Antibody

Code CSB-PA010031LA01HU
Size US$166
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Image
  • IHC image of CSB-PA010031LA01HU diluted at 1:500 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Immunofluorescence staining of 293 cells with CSB-PA010031LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GTPBP1 Polyclonal antibody
Uniprot No.
Target Names
GTPBP1
Alternative Names
G protein 1 antibody; G-protein 1 antibody; GP 1 antibody; GP-1 antibody; GP1 antibody; GTP binding protein 1 antibody; GTP-binding protein 1 antibody; GTPB1_HUMAN antibody; GTPBP1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GTP-binding protein 1 protein (562-669AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GTPBP1 Antibody (Product code: CSB-PA010031LA01HU) is Non-conjugated. For GTPBP1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010031LB01HU GTPBP1 Antibody, HRP conjugated ELISA
FITC CSB-PA010031LC01HU GTPBP1 Antibody, FITC conjugated
Biotin CSB-PA010031LD01HU GTPBP1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:500-1:1000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.
Gene References into Functions
  1. GTPBP1 possesses eEF1A-like elongation activity, delivering cognate aminoacyl-transfer RNA to the ribosomal A site in a GTP-dependent manner. It also stimulates exosomal degradation of mRNAs in elongation complexes. PMID: 30108131
Subcellular Location
Cytoplasm.
Protein Families
TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, GTPBP1 subfamily
Database Links

HGNC: 4669

OMIM: 602245

KEGG: hsa:9567

STRING: 9606.ENSP00000216044

UniGene: Hs.276925

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