Gp2 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA880511LD01MO
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Gp2 Polyclonal antibody

Uniprot No.

Q9D733

Target Names

Gp2

Alternative Names

Gp2 antibody; Pancreatic secretory granule membrane major glycoprotein GP2 antibody; Pancreatic zymogen granule membrane protein GP-2 antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 protein (22-531AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participate in the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.

Gene References into Functions

GP2 is a popular secretory product released from mucous glands and secretory cells and may support defense mechanisms against pathogenic bacteria in the tubular organs open to the external milieu. PMID: 28003582
GP2-expressing cells in paranasal sinuses are in the lineage of goblet cells. PMID: 25355440
Tightly linked to homologue THP. A Gp2 knockout mouse was established which does express THP. PMID: 15325280
unlikely that GP2 serves a major intracellular role within the acinar cell, may be active after it is secreted PMID: 15385539
glycoprotein 2 (GP2), specifically expressed on the apical plasma membrane of M cells among enterocytes, serves as a transcytotic receptor for mucosal antigens PMID: 19907495

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Subcellular Location

Zymogen granule membrane; Lipid-anchor, GPI-anchor. Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-anchor. Endosome.

Tissue Specificity

Specifically expressed by M (microfold) cells which are atypical epithelial cells of the intestine.

Database Links

KEGG: mmu:67133

STRING: 10090.ENSMUSP00000033255

UniGene: Mm.46403

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Homeobox Transcription Factor- NANOG The Overview of Phage Display: Protocol, Classification, Application and FAQs Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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