Gripap1 Antibody

Code CSB-PA210251
Size US$297
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  • Western blot analysis of extracts from rat brain and mouse brain tissue using GRASP Antibody
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Product Details

Full Product Name
Rabbit anti-Rattus norvegicus (Rat) Gripap1 Polyclonal antibody
Uniprot No.
Target Names
Gripap1
Alternative Names
Gripap1 antibody; Grasp1GRIP1-associated protein 1 antibody; GRASP-1) [Cleaved into: GRASP-1 C-terminal chain antibody; 30kDa C-terminus form)] antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP.
Immunogen Species
Rattus norvegicus (Rat)
Clonality
Polyclonal
Purification Method
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of recycling endosomes from early endosomal membranes. Involved in the localization of recycling endosomes to dendritic spines, thereby playing a role in the maintenance of dendritic spine morphology. Required for the activity-induced AMPA receptor recycling to dendrite membranes and for long-term potentiation and synaptic plasticity.; Functions as a scaffold protein in neurons to facilitate MAP3K1/MEKK1-mediated activation of the JNK1 kinase by phosphorylation, possibly by bringing MAP3K1/MEKK1 and JNK1 in close proximity.
Subcellular Location
Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse.
Tissue Specificity
Expressed in the central nervous system; especially in neurons.
Database Links

KEGG: rno:116493

UniGene: Rn.53868

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