HAAO Antibody

Datasheet

Code	CSB-PA010112LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA010112LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA010112LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HAAO Polyclonal antibody

Uniprot No.

P46952

Target Names

HAAO

Alternative Names

3 HAO antibody; 3 hydroxyanthranilate 3 4 dioxygenase antibody; 3 hydroxyanthranilate dioxygenase antibody; 3 hydroxyanthranilate oxygenase antibody; 3 hydroxyanthranilic acid dioxygenase antibody; 3-HAO antibody; 3-hydroxyanthranilate 3,4-dioxygenase antibody; 3-hydroxyanthranilate oxygenase antibody; 3-hydroxyanthranilic acid dioxygenase antibody; 3HAO_HUMAN antibody; haao antibody; HAD antibody; HAO antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human 3-hydroxyanthranilate 3,4-dioxygenase protein (153-223AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The HAAO Antibody (Product code: CSB-PA010112LA01HU) is Non-conjugated. For HAAO Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA010112LB01HU	HAAO Antibody, HRP conjugated	ELISA
FITC	CSB-PA010112LC01HU	HAAO Antibody, FITC conjugated
Biotin	CSB-PA010112LD01HU	HAAO Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

Gene References into Functions

Here, the first crystal structure of human 3-HAO with the native iron bound in its active site is presented, together with an additional structure with zinc (a known inhibitor of human 3-HAO) bound in the active site. PMID: 28375145
Methylation status of CIDEA, HAAO and RXFP3 had significant association with microsatellite instability in endometrial tumors. PMID: 20211485
GTF2A1 alone, or GTF2A1 plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer PMID: 19724865

Subcellular Location

Cytoplasm, cytosol.

Protein Families

3-HAO family

Database Links

HGNC: 4796

OMIM: 604521

KEGG: hsa:23498

STRING: 9606.ENSP00000294973

UniGene: Hs.368805

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Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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