HAAO Antibody, HRP conjugated

Code CSB-PA010112LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HAAO Polyclonal antibody
Uniprot No.
Target Names
HAAO
Alternative Names
3 HAO antibody; 3 hydroxyanthranilate 3 4 dioxygenase antibody; 3 hydroxyanthranilate dioxygenase antibody; 3 hydroxyanthranilate oxygenase antibody; 3 hydroxyanthranilic acid dioxygenase antibody; 3-HAO antibody; 3-hydroxyanthranilate 3,4-dioxygenase antibody; 3-hydroxyanthranilate oxygenase antibody; 3-hydroxyanthranilic acid dioxygenase antibody; 3HAO_HUMAN antibody; haao antibody; HAD antibody; HAO antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 3-hydroxyanthranilate 3,4-dioxygenase protein (153-223AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
Gene References into Functions
  1. Here, the first crystal structure of human 3-HAO with the native iron bound in its active site is presented, together with an additional structure with zinc (a known inhibitor of human 3-HAO) bound in the active site. PMID: 28375145
  2. Methylation status of CIDEA, HAAO and RXFP3 had significant association with microsatellite instability in endometrial tumors. PMID: 20211485
  3. GTF2A1 alone, or GTF2A1 plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer PMID: 19724865
Subcellular Location
Cytoplasm, cytosol.
Protein Families
3-HAO family
Database Links

HGNC: 4796

OMIM: 604521

KEGG: hsa:23498

STRING: 9606.ENSP00000294973

UniGene: Hs.368805

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