HAAO Antibody

Code CSB-PA010112GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HAAO
Alternative Names
3 HAO antibody; 3 hydroxyanthranilate 3 4 dioxygenase antibody; 3 hydroxyanthranilate dioxygenase antibody; 3 hydroxyanthranilate oxygenase antibody; 3 hydroxyanthranilic acid dioxygenase antibody; 3-HAO antibody; 3-hydroxyanthranilate 3,4-dioxygenase antibody; 3-hydroxyanthranilate oxygenase antibody; 3-hydroxyanthranilic acid dioxygenase antibody; 3HAO_HUMAN antibody; haao antibody; HAD antibody; HAO antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HAAO
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
Gene References into Functions
  1. Here, the first crystal structure of human 3-HAO with the native iron bound in its active site is presented, together with an additional structure with zinc (a known inhibitor of human 3-HAO) bound in the active site. PMID: 28375145
  2. Methylation status of CIDEA, HAAO and RXFP3 had significant association with microsatellite instability in endometrial tumors. PMID: 20211485
  3. GTF2A1 alone, or GTF2A1 plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer PMID: 19724865
Subcellular Location
Cytoplasm, cytosol.
Protein Families
3-HAO family
Database Links

HGNC: 4796

OMIM: 604521

KEGG: hsa:23498

STRING: 9606.ENSP00000294973

UniGene: Hs.368805

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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