HARS2 Antibody

Code CSB-PA010138GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HARS2
Alternative Names
4631412B19Rik antibody; AI593507 antibody; HARS related antibody; Hars2 antibody; HARSL antibody; HARSR antibody; HisRS antibody; Histidine translase antibody; Histidine tRNA ligase antibody; Histidine tRNA ligase homolog antibody; Histidine tRNA ligase like antibody; Histidine--tRNA ligase antibody; Histidine--tRNA ligase-like antibody; Histidyl tRNA synthetase 2 antibody; Histidyl tRNA synthetase 2 mitochondrial antibody; Histidyl tRNA synthetase like antibody; HO3 antibody; mitochondrial antibody; Probable histidyl tRNA synthetase mitochondrial antibody; Probable histidyl-tRNA synthetase antibody; SYHM_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HARS2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mitochondrial aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP).
Gene References into Functions
  1. Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. PMID: 21464306
  2. This protein has been found differentially expressed in the anterior cingulate cortex in men patients with schizophrenia. PMID: 20381070
Involvement in disease
Perrault syndrome 2 (PRLTS2)
Subcellular Location
Mitochondrion.
Protein Families
Class-II aminoacyl-tRNA synthetase family
Tissue Specificity
A high level expression is seen in the heart, kidney and skeletal muscle while a lower level expression is seen in the brain and liver.
Database Links

HGNC: 4817

OMIM: 600783

KEGG: hsa:23438

STRING: 9606.ENSP00000230771

UniGene: Hs.432560

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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