HAUS8 Antibody

Code CSB-PA863116ESR1HU
Size US$166
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Image
  • Western blot
    All lanes: HAUS8 antibody at 2.35 μg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse brain tissue
    Lane 3: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 45, 39 kDa
    Observed band size: 45, 50, 28 kDa

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA863116ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA863116ESR1HU at dilution of 1:100

  • Immunofluorescent analysis of PC-3 cells using CSB-PA863116ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HAUS8 Polyclonal antibody
Uniprot No.
Target Names
HAUS8
Alternative Names
DGT4 antibody; HAUS augmin like complex subunit 8 antibody; HAUS augmin-like complex subunit 8 antibody; HAUS8 antibody; HAUS8_HUMAN antibody; Hec1 interacting and centrosome associated 1 antibody; HEC1/NDC80 interacting centrosome associated protein 1 antibody; HEC1/NDC80-interacting centrosome-associated protein 1 antibody; HICE 1 antibody; HICE1 antibody; MGC20533 antibody; NY SAR 48 antibody; NY-SAR-48 antibody; Sarcoma antigen NY SAR 48 antibody; Sarcoma antigen NY-SAR-48 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human HAUS augmin-like complex subunit 8 protein (166-410AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Gene References into Functions
  1. Aurora-A modulates the microtubule binding activity of Hice1 in a spatiotemporal manner for proper bipolar spindle assembly. PMID: 21705324
  2. Results suggest that Hec1, through cooperation with Hice1, contributes to centrosome-directed microtubule growth to facilitate establishing a proper mitotic spindle. PMID: 19776357
  3. Hice1 is a novel microtubule-associated protein important for maintaining spindle integrity and chromosomal stability, in part by virtue of its ability to bind, bundle, and stabilize microtubules. PMID: 18362163
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Protein Families
HAUS8 family
Database Links

HGNC: 30532

OMIM: 613434

KEGG: hsa:93323

STRING: 9606.ENSP00000253669

UniGene: Hs.404088

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