HECTD2 Antibody, FITC conjugated

Code CSB-PA732977LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HECTD2 Polyclonal antibody
Uniprot No.
Target Names
HECTD2
Alternative Names
FLJ16050 antibody; FLJ37306 antibody; HECD2_HUMAN antibody; HECT domain containing 2 antibody; HECT domain containing protein 2 antibody; HECT domain-containing protein 2 antibody; Hectd2 antibody; OTTHUMP00000020086 antibody; OTTHUMP00000038605 antibody; Probable E3 ubiquitin protein ligase HECTD2 antibody; Probable E3 ubiquitin-protein ligase HECTD2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable E3 ubiquitin-protein ligase HECTD2 protein (674-776AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.; (Microbial infection) Catalyzes ubiquitination of Botulinum neurotoxin A light chain (LC) of C.botulinum neurotoxin type A (BoNT/A).
Gene References into Functions
  1. A major biological consequence of upregulation of miR-221 is reprogramming of androgen receptor signaling via downregulation of HECTD2 and RAB1A. PMID: 23770851
  2. HECTD2 polymorphisms are not associated with genetic susceptibility to sporadic Creutzfeldt-Jakob disease in a Korean population PMID: 21335971
  3. HECTD2 haplotypes are associated with the susceptibility to human prion diseases. PMID: 19214206
  4. The common haplotypes of HECTD2, tagged by rs12249854, are not associated with susceptibility to late onset Alzheimer's disease PMID: 19754925
Database Links

HGNC: 26736

KEGG: hsa:143279

STRING: 9606.ENSP00000298068

UniGene: Hs.596096

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