HLA-DMA Antibody, FITC conjugated

Code CSB-PA338892LC01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) HLA-DMA Polyclonal antibody
Uniprot No. P28067
Target Names HLA-DMA
Alternative Names HLA-DMA antibody; DMA antibody; RING6HLA class II histocompatibility antigen antibody; DM alpha chain antibody; MHC class II antigen DMA antibody; Really interesting new gene 6 protein antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA)
Immunogen Species Homo sapiens (Human)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Subcellular Location Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Protein Families MHC class II family
Database Links

HGNC: 4934

OMIM: 142855

STRING: 9606.ENSP00000363976

UniGene: Hs.728759

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