HOXB2 Antibody

Datasheet

Code	CSB-PA106653
Size	US$297
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Image	Western blot analysis of extracts from LOVO cells, A549 cells, HUVEC cells and MCF-7 cells, using HOXB2 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HOXB2 Polyclonal antibody

Uniprot No.

P14652

Target Names

HOXB2

Alternative Names

homeo box 2H antibody; homeo box B2 antibody; homeobox B2 antibody; Homeobox protein Hox-2.8 antibody; Homeobox protein Hox-2H antibody; Homeobox protein Hox-B2 antibody; Hox 2 8 antibody; Hox 2H antibody; HOX2 antibody; HOX2H antibody; hoxb2 antibody; HXB2_HUMAN antibody; K8 antibody; K8 home protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human HOXB2.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Gene References into Functions

HOXB2 and HOXB3 act as tumor suppressors in acute myeloid leukemia patients carrying the FLT3 protein mutations. PMID: 26482852
Increased expression of HOXB2 protein is associated with HPV infection and cervical cancer progression. PMID: 25743797
HOXB2 acts as a negative tumor growth regulator, decreasing proliferation in mammary adenocarcinoma tumors. PMID: 21672623
hoxb2 and hoxb4 expression is related to erythroid hematopoiesis, and hoxb4 has greater relevance to erythroid hematopoiesis as compared with hoxb2. PMID: 20030938
Downregulation of HoxB2, HoxB4 and Alx4 expression during the narrow window of early embryogenesis may cause omphalocele in the Cd chick model by interfering with molecular signaling required for proper VBW formation. PMID: 20625746
Hoxb2 is a direct target for regulation by PLZF in the developing CNS and suggest that deregulation of Hox gene expression may contribute to APL pathogenesis. PMID: 12802276
HOXB2 up-regulated lesions to have much higher HOXB2 expression than the corresponding normal tissue. PMID: 17805056

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Subcellular Location

Nucleus.

Protein Families

Antp homeobox family, Proboscipedia subfamily

Database Links

HGNC: 5113

OMIM: 142967

KEGG: hsa:3212

STRING: 9606.ENSP00000331741

UniGene: Hs.514289

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Service

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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