HOXC4 Antibody

Datasheet

Code	CSB-PA010675GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P09017

Target Names

HOXC4

Alternative Names

CP 19 antibody; CP19 antibody; Homeo box 3E antibody; Homeo box C4 antibody; Homeo box protein HoxC4 antibody; Homeobox 3E antibody; Homeobox C4 antibody; Homeobox protein CP19 antibody; Homeobox protein Hox C4 antibody; Homeobox protein Hox-3E antibody; Homeobox protein Hox-C4 antibody; Homeobox protein HoxC4 antibody; Homeobox3E antibody; HomeoboxC4 antibody; HOX 3 antibody; Hox 3E antibody; HOX C4 antibody; HOX3 antibody; Hox3E antibody; HOXC 4 antibody; Hoxc4 antibody; HXC4_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human HOXC4

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Gene References into Functions

HOXC4 homeoprotein expands human hematopoietic immature cells by 3 to 6 times ex vivo and significantly improves the level of in vivo engraftment. PMID: 22298821
Human cytomegalovirus downregulates while all-trans retinoic acid upregulates expression of hoxc4 and hoxc6 in lymphocytic progenitor cells. PMID: 19236766
Esr1 bind to and activate the HOXC4 promoter to potentiate HoxC4-mediated AID induction, immunoglobulin class switch and somatic hypermutation. PMID: 20855884
Selective inhibition of class switching to IgG and IgE by recruitment of this and Oct-1 proteins and Ku70/Ku86 to newly identified ATTT cis-elements. PMID: 12672812
The hs1,2mediated enhancement of V(H) and C(H) promoter-driven transcription as induced by HoxC4 and Oct-1/Oct-2 suggests an important role of these homeodomain proteins in the overall regulation of the IgH locus expression. PMID: 15252056
The HOXC4 expression was clearly detected in all inv(7) positive patients. PMID: 15674412
HoxC4 directly activates the Aicda promoter PMID: 19363484

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Subcellular Location

Nucleus.

Protein Families

Antp homeobox family, Deformed subfamily

Database Links

HGNC: 5126

OMIM: 142974

KEGG: hsa:3221

STRING: 9606.ENSP00000305973

UniGene: Hs.549040

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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