HOXC9 Antibody

1. HOXC9 knockdown inhibited the metastasis and stem cell-like phenotype of GC cells without significant effects on cell proliferation as a direct target of miR-26a. PMID: 30205370
2. downregulation of HOXC9 releases its transcriptional inhibition of DAPK1, resulting in the activation of the DAPK1-Beclin1 pathway, which induces autophagy in glioblastoma cells PMID: 26582930
3. HOXC9 and HOXC10 may play an important role in the development of obesity, adverse fat distribution, and subsequent alterations in whole-body metabolism and adipose tissue function. PMID: 26647900
4. Results provide a set of the essential genes in the miR-193a-3p/HOXC9/DNA damage response/oxidative stress pathway axis as the diagnostic targets for the guided anti-bladder cancer chemotherapy. PMID: 25444900
5. HOXC9 coordinates diverse cellular processes associated with differentiation by directly activating and repressing the transcription of distinct sets of genes. PMID: 24274069
6. HoxC9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma. PMID: 23579273
7. We did not find any potential pathological mutations in the Hoxc9 gene among Chinese patients with congenital heart disease. PMID: 22106857
8. The data identify HOXC9 as an endothelial cell active transcriptional repressor promoting the resting, antiangiogenic endothelial cell phenotype in an interleukin 8-dependent manner PMID: 21493894
9. HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma. PMID: 21507931
10. Up-regulation of HOXC9 was detected in a set of 54 astrocytomas of different grades and significantly associated with malignancy. PMID: 17588684
11. Methylated state of this set of genes may be more specific to the late rather than the early stage of NSCLC. PMID: 19506903

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HGNC: 5130

OMIM: 142971

KEGG: hsa:3225

STRING: 9606.ENSP00000302836

UniGene: Hs.658823