HSPA12A Antibody

Code CSB-PA010817LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: SH-SY5Y whole cell lysate, 293 whole cell lysate, HepG2 whole cell lysate
    All lanes: HSPA12A antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 75 kDa
    Observed band size: 75 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HSPA12A Polyclonal antibody
Uniprot No.
Target Names
HSPA12A
Alternative Names
FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; heat shock 70kD protein 12A antibody; heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Heat shock 70 kDa protein 12A protein (2-231AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HSPA12A Antibody (Product code: CSB-PA010817LA01HU) is Non-conjugated. For HSPA12A Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010817LB01HU HSPA12A Antibody, HRP conjugated ELISA
FITC CSB-PA010817LC01HU HSPA12A Antibody, FITC conjugated
Biotin CSB-PA010817LD01HU HSPA12A Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
Gene References into Functions
  1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
  2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
  3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Heat shock protein 70 family
Tissue Specificity
Widely expressed with highest levels in brain, kidney and muscle.
Database Links

HGNC: 19022

OMIM: 610701

KEGG: hsa:259217

STRING: 9606.ENSP00000358211

UniGene: Hs.648448

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