Histone H3 Antibody

Datasheet
Code CSB-PA080208
Size US$167
Uniprot No. P68431
Image
  • Immunohistochemical analysis of paraffin-embedded human Breast caricnoma using Histone H3 Polyclonal Antibody.

  • Western blot analysis of 1) Hela, 2) 3T3 using Histone H3 Polyclonal Antibody.

Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Synthetic Peptide
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,IHC;WB:1:500-1000.IHC:1:200-500
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Isotype IgG
Alias Histone H3.1
Immunogen Species Homo sapiens (Human)
Target Names HIST1H3A
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Involvement in disease Glioma (GLM)
Subcellular Location Nucleus, Chromosome
Protein Families Histone H3 family
Database Links

HGNC: 4766

OMIM: 137800

KEGG: hsa:8350

STRING: 9606.ENSP00000444823

UniGene: Hs.132854

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