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Hpx Antibody

Rare Species
Datasheet
Code CSB-PA010723LA01RA
Size US$166
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Image
  • Western Blotting(WB) - Hpx Antibody
    Western blot
    All lanes: Hpx antibody at 4.5µg/ml + HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 52 kDa
    Observed band size: 52 kDa
  • Immunohistochemistry of paraffin-embedded Mouse live tissue using CSB-PA010723LA01RA at dilution of 1:200
  • Immunohistochemistry of paraffin-embedded Human live tissue using CSB-PA010723LA01RA at dilution of 1:200
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Product Details

Full Product Name
Rabbit anti-Rattus norvegicus (Rat) Hpx Polyclonal antibody
Uniprot No.
P20059
Target Names
Hpx
Alternative Names
Hpx antibody; Hemopexin antibody
Raised in
Rabbit
Species Reactivity
Rat, Human
Immunogen
Recombinant Rat Hemopexin protein (24-460AA)
Immunogen Species
Rattus norvegicus (Rat)
Conjugate
Non-conjugated

The Hpx Antibody (Product code: CSB-PA010723LA01RA) is Non-conjugated. For Hpx Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010723LB01RA Hpx Antibody, HRP conjugated ELISA
FITC CSB-PA010723LC01RA Hpx Antibody, FITC conjugated
Biotin CSB-PA010723LD01RA Hpx Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Gene References into Functions
  1. Data suggest that apo-hemopexin isolated from plasma exchibits low endogenous levels of tyrosine nitration in the peptide YYCFQGNQFLR in the heme-binding site of human hemopexin, which was similarly nitrated in rabbit and rat hemopexins; heme binding by hemopexin declined as tyrosine nitration proceeded in vitro. PMID: 28596380
  2. Hemopexin was identified as upregulated protein in the small intestine exposed to indomethacin. PMID: 22486875
  3. hemopexin mRNA was low or undetectable in livers of hypophysectomized rats, however, daily treatment with bovine growth hormone for 10 days restored hemopexin mRNA levels PMID: 12850285
  4. intracellular calcium and protein kinase C activation are involved in the regulation of Hpx. PMID: 12850286
Subcellular Location
Secreted.
Protein Families
Hemopexin family
Tissue Specificity
Expressed by the liver and secreted in plasma.
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